The Hallmarks of Cancer is a landmark review article. The authors found and cited other studies and put it together in an article known as a review article. Read the Hallmarks of Cancer posted on Cougar courses. For this assignment you will also need to use and site a primary source/article. A primary peer-reviewed article is not a review article; it contains original research that has not been previously published. In order to find primary peer-reviewed articles you will need to use pubmed.gov or google scholar. Wiki-anything is not primary sources. In the Hallmarks of Cancer you will notice when they cite someone else’s work they end the sentence (Last name, Year of publication). Please do the same in this writing assignment and in your Cancer Brochure assignment. This writing assignment will provide some foundational information that you will be able to utilize in your cancer brochure.
1. List the specific hallmarks of cancer discussed in the review article, ranking them in order of which you think should be the focus of more investigation in an effort to develop more therapeutic options for patients.
- Select one of the hallmarks of cancer and describe in detail what occurs in that hallmark towards carcinogenesis. Make sure to mention genes and mutations that contribute to that process. I highly recommend, (if possible) you make an effort to find a gene and mutation that occurs in the cancer for your Cancer Brochure assignment. Identify a gene and mutation that is involved in the carcinogenesis hallmark that is NOT mentioned in the review article. If the specific cancer mutation you found for your cancer is not mentioned in the review article you do not need to find a new one. If the specific cancer mutation and the hallmark mutation are in the same gene/mutation find an additional gene and/or mutation. How prevalent is that mutation in your cancer of interest? Is it a specific mutation in the gene that leads to its effect or does the cancer alter the gene with a plethora of different mutations in different patients? Now that you know a lot more about this hallmark and your cancer, search and find if there are therapeutics for your hallmark. What is the therapeutic? Is it a specific therapeutic for the hallmark that can be used for multiple cancers? Or is it specifically used to treat your cancer of interest and not specifically the hallmark? How do patients receive that therapy?
- Do you think there is a “silver bullet” cancer therapeutic that has yet to be discovered? By silver bullet I mean a cure that would work for all cancers. Please provide an explanation for your answer.
When you are citing someone else’s work paraphrase do not quote and cite at the end of the sentence (last name of last author and year it was published).
Compelling correspondence is essential to the achievement all things considered but since of the changing idea of the present working environments, successful correspondence turns out to be more troublesome, and because of the numerous impediments that will permit beneficiaries to acknowledge the plan of the sender It is restricted. Misguided judgments.In spite of the fact that correspondence inside the association is rarely completely open, numerous straightforward arrangements can be executed to advance the effect of these hindrances.
Concerning specific contextual analysis, two significant correspondence standards, correspondence channel determination and commotion are self-evident. This course presents the standards of correspondence, the act of general correspondence, and different speculations to all the more likely comprehend the correspondence exchanges experienced in regular daily existence. The standards and practices that you learn in this course give the premise to additionally learning and correspondence.
This course starts with an outline of the correspondence cycle, the method of reasoning and hypothesis. In resulting modules of the course, we will look at explicit use of relational connections in close to home and expert life. These incorporate relational correspondence, bunch correspondence and dynamic, authoritative correspondence in the work environment or relational correspondence. Rule of Business Communication In request to make correspondence viable, it is important to follow a few rules and standards. Seven of them are fundamental and applicable, and these are clear, finished, brief, obliging, right, thought to be, concrete. These standards are frequently called 7C for business correspondence. The subtleties of these correspondence standards are examined underneath: Politeness Principle: When conveying, we should build up a cordial relationship with every individual who sends data to us.
To be inviting and polite is indistinguishable, and politeness requires an insightful and amicable activity against others. Axioms are notable that gracious “pay of graciousness is the main thing to win everything”. Correspondence staff ought to consistently remember this. The accompanying standards may assist with improving courtesy:Preliminary considering correspondence with family All glad families have the mystery of progress. This achievement originates from a strong establishment of closeness and closeness. Indeed, through private correspondence these cozy family connections become all the more intently. Correspondence is the foundation of different affiliations, building solid partners of obedient devotion, improving family way of life, and assisting with accomplishing satisfaction (Gosche, p. 1). In any case, so as to keep up an amicable relationship, a few families experienced tumultuous encounters. Correspondence in the family is an intricate and alluring marvel. Correspondence between families isn’t restricted to single messages between families or verbal correspondence.
It is a unique cycle that oversees force, closeness and limits, cohesiveness and flexibility of route frameworks, and makes pictures, topics, stories, ceremonies, rules, jobs, making implications, making a feeling of family life An intelligent cycle that makes a model. This model has passed ages. Notwithstanding the view as a family and family automatic framework, one of the greatest exploration establishments in between family correspondence centers around a family correspondence model. Family correspondence model (FCP) hypothesis clarifies why families impart in their own specific manner dependent on one another ‘s psychological direction. Early FCP research established in media research is keen on how families handle broad communications data. Family correspondence was perceived as an exceptional scholastic exploration field by the National Communications Association in 1989. Family correspondence researchers were at first impacted by family research, social brain science, and relational hypothesis, before long built up the hypothesis and began research in a family framework zeroed in on a significant job. Until 2001, the primary issue of the Family Communication Research Journal, Family Communication Magazine, was given. Family correspondence is more than the field of correspondence analysts in the family. Examination on family correspondence is normally done by individuals in brain science, humanism, and family research, to give some examples models. However, as the popular family correspondence researcher Leslie Baxter stated, it is the focal point of this intelligent semantic creation measure making the grant of family correspondence special. In the field of in-home correspondence, correspondence is normally not founded on autonomous messages from one sender to one beneficiary, yet dependent on the dynamic interdependency of data shared among families It is conceptualized. The focal point of this methodology is on the shared trait of semantic development inside family frameworks. As such, producing doesn’t happen in vacuum, however it happens in a wide scope of ages and social exchange.
Standards are rules end up being followed when performing work to agree to a given objective. Hierarchical achievement relies significantly upon compelling correspondence. So as to successfully impart, it is important to follow a few standards and rules. Coming up next are rules to guarantee powerful correspondence: clearness: lucidity of data is a significant guideline of correspondence. For beneficiaries to know the message plainly, the messages ought to be sorted out in a basic language. To guarantee that beneficiaries can without much of a stretch comprehend the importance of the message, the sender needs to impart unmistakably and unhesitatingly so the beneficiary can plainly and unquestionably comprehend the data.>