Appropriate drug therapy for a patient who presents with MDD and a history of alcohol abuse.

In 3 or 4 sentences, explain the appropriate drug therapy for a patient who presents with MDD and a history of alcohol abuse. Which drugs are contraindicated, if any, and why? Be specific. What is the timeframe that the patient should see resolution of symptoms? List 4 predictors of late onset generalized anxiety disorder. List 4 potential neurobiology causes of psychotic major depression.